True Blue offers some of the most comprehensive Genetic testing available with its True Blueprint® Genetic Tests. These once in a lifetime tests are the future of preventative healthcare
This extensive compilation of tests can be taken with just a few cheek swabs!
· Cancer & Cardiac Status
· Carrier Status
· Healthy Weight Personal Profile
· Genetically Matched Diet Personal Profile
· Pharmacogenetics (PGx) Personal Profile
· Results in 6-8 weeks
· Call with a geneticist to review results
· RESULTS ARE 100% CONFIDENTIAL
The True Blueprint® Genetic tests are ordered by a physician. Your own doctor can do this for you, or True Blue can have an independent physician review your information and order your test, if appropriate.
Genes are instructions, written in DNA, for building protein molecules. Different people can have different versions — slightly different DNA sequences — of the same gene. Some of these variations are common and some are rare. Some are relevant for health, such as those associated with a tendency to develop certain diseases.
Healthy Weight Personal Profile is a comprehensive health and wellness genetic test that provides a unique combination of information regarding nutrigenetics, medication response, and a number of common health conditions. Using a proprietary algorithm, this test also provides a genetically-matched diet allowing patients to make educated decisions to help achieve or maintain a healthy weight.
Cardiac Status helps identify 23 traits associated with an increased risk of developing certain heart-related health conditions, and provides insight into your potential responses to commonly prescribed medications, so your physician can develop a more personalized treatment for you.
Carrier Status allows patients to gain knowledge on their risks of passing inheritable genetic diseases to their children or future children. A more comprehensive assessment can be obtained if both parents are tested.
Understanding Carrier Status
Each person has two copies of the genetic materials, one copy inherited from each parent. Many genetic diseases are recessive, meaning the disease is caused by inheriting a mutation at the same DNA location from both parents. If a parent carries a mutation in one of the two copies of the DNA, he/she is a carrier of the genetic disease.
A carrier has a 50% chance of passing the same mutation to the child. If both parents are carriers, the child will have a 25% chance of inheriting both copies of the mutation, thus leading to the development of the genetic disease. Some inherited diseases are more common in certain ethnic groups and in people with a family history of genetic disorders.
Cancer Status can be used to test for a set of genomic markers (ctDNA) that have previously been associated with a number of different cancer types. The presence of one or more of these genomic markers in a patient’s sample may indicate that the patient has a tumor that is shedding ctDNA into the blood stream. However, the test is not diagnostic, and thus, follow-up screening and clinical testing would be required to confirm the presence or absence of a specific cancer in the patient.
This test works by analyzing cell-free DNA (cfDNA). It detects the presence of specific genomic markers called circulating tumor DNA (ctDNA) in 9 cancer driver genes. This test analyzes 96 tumor markers in 9 cancer driver genes.
Pharmacogenetics (PGx) Personal Profile (sometimes called pharmacogenomics) is a field of research focused on understanding how genes affect individual responses to medications. This helps doctors select the drugs and dosages best suited for each person.
Pharmacogenetics looks at variations in genes for proteins that influence drug responses. Such proteins include several liver enzymes that convert medications into their active or inactive forms. Even small differences in the genetic sequences of these enzymes can have a big impact on a drug’s safety or effectiveness.
The Food and Drug Administration, which monitors the safety of all drugs in the United States, has included pharmacogenetics information on the labels of more than 150 medications. This information — which can cover dosage guidance, possible side effects or differences in effectiveness for people with certain genomic variations — can help doctors tailor their drug prescriptions for individual patients.
Currently, doctors base most their drug prescriptions on clinical factors, such as a patient’s age, weight, sex, and liver and kidney function. For a small subset of drugs, researchers have identified genetic variations that influence how people respond. In these cases, doctors can use the pharmacogenetics information to select the best medication and identify people who need an unusually high or low dose.
* Applicants must be 18 years age, have a valid ID and valid insurance card.
* Genetics Testing will be submitted to applicant’s insurance for reimbursement.
* Verification of insurance coverage will be performed before genetics test is processed. In the event that no coverage exists the genetic test will not be processed and no cost will be incurred by the applicant.
* The above is only informational and should not substitute the advice of a genetic counselor or licensed physician.